BDBM14363 3-(2-propoxyphenyl)-2,4,7,8,9-pentazabicyclo[4.3.0]nona-1,3,6-trien-5-one::5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one::Tocris-0947::Zaprinast
SMILES CCCOc1ccccc1-c1nc2nn[nH]c2c(=O)[nH]1
InChI Key InChIKey=REZGGXNDEMKIQB-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 24 hits for monomerid = 14363
Affinity DataKi: 401nMAssay Description:Displacement of [3H]PSB-13253 from human recombinant GPR35 exprssed in CHO cells by liquid scintillation counting analysisChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataEC50: 140nMAssay Description:Agonist activity at GPR35 in human HT-29 cells measured after 10 mins by dynamic mass redistribution assayMore data for this Ligand-Target Pair
Affinity DataEC50: 4.20E+3nMAssay Description:Agonist activity at GPR35 in human U20S cells expressing beta-lactamase and GPR35-GA14-VP16 transcription factor fusion protein assessed as transcrip...More data for this Ligand-Target Pair
Affinity DataEC50: 160nMAssay Description:Agonist activity at GPR35 in human HT-29 cells after 1 hr by dynamic mass redistribution assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.05E+4nMAssay Description:Antagonist activity at GPR35 in human HT-29 cells assessed as inhibition of zaprinast-induced DMR by dynamic mass redistribution assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.22E+3nMAssay Description:Agonist activity at GPR35 in human HT-29 cells assessed as desensitization of 1 uM zaprinast-induced DMR after 1 hr by dynamic mass redistribution as...More data for this Ligand-Target Pair
Affinity DataEC50: 130nMAssay Description:Agonist activity at human GPR35 by Ca+2 release assayChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataEC50: 2.24E+3nMAssay Description:Agonist activity at human GPR35b expressed in CHO cells assessed as induction of beta-arrestin recruitment after 90 mins by beta-galactosidase report...More data for this Ligand-Target Pair
Affinity DataEC50: 980nMAssay Description:Agonist activity at mouse GPR35 expressed in CHO cells assessed as induction of beta-arrestin recruitment after 90 mins by beta-galactosidase reporte...More data for this Ligand-Target Pair
Affinity DataEC50: 1.96E+3nMAssay Description:Agonist activity at human GPR35 expressed in CHO cells assessed as induction of beta-arrestin recruitment after 90 mins by beta-galactosidase reporte...More data for this Ligand-Target Pair
Affinity DataEC50: 5.30E+3nMAssay Description:Agonist activity at human GPR35 expressed in U2OS cells coexpressing Gal4-VP16/beta-arrestin fusion protein after 5 hrs by tango beta-arrestin transl...More data for this Ligand-Target Pair
Affinity DataEC50: 160nMAssay Description:Agonist activity at GPR35 in human HT-29 cells by dynamic mass redistribution assayMore data for this Ligand-Target Pair
Affinity DataEC50: 6.20E+3nMAssay Description:Agonist activity at GPR35 in human U20S cells expressing beta-lactamase and Gal4-VP16 transcription factor assessed as beta arrestin translocation af...More data for this Ligand-Target Pair
Affinity DataEC50: 160nMAssay Description:Agonist activity at GPR35 receptor in human HT-29 cells after 10 mins by dynamic mass redistribution assayMore data for this Ligand-Target Pair
Affinity DataEC50: 6.10E+3nMAssay Description:Agonist activity at GPR35 receptor in human U2OS cells coexpressing Gal4-VP16-TEV assessed as beta arrestin translocation after 5 hrs by beta lactmas...More data for this Ligand-Target Pair
Affinity DataIC50: 1.22E+3nMAssay Description:Desensitization of GPR35 receptor in human HT-29 cells assessed as inhibition of zaprinast-induced dynamic mass redistribution after 10 minsMore data for this Ligand-Target Pair
Affinity DataEC50: 3.52E+3nMAssay Description:Agonist activity at TEV protease cleavage site linked GAL4-VP16-fused GPR35 in human Tango GPR35-bla U2OS cells assessed as induction of TEV protease...More data for this Ligand-Target Pair
Affinity DataEC50: 2.00E+3nMAssay Description:Agonist activity at human GPR35 assessed as induction of beta-arrestin recruitmentMore data for this Ligand-Target Pair
Affinity DataEC50: 340nMAssay Description:Agonist activity at GPR35 in human HT-29 cells by DMR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 160nMAssay Description:Agonist activity at GPR35 in human HT-29 cells by DMR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 4.20E+3nMAssay Description:Agonist activity at GPR35 in human HT-29 cells by DMR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 340nMAssay Description:Agonist activity at human GPR35 receptor expressed in HT-29 cells assessed as dynamic mass redistribution response by DMR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 63nMAssay Description:Agonist activity at human GPR35 receptor expressed in CHO-K1 cells assessed as dynamic mass redistribution response by DMR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Agonist activity at human GPR35 receptor expressed in CHO-K1 cells assessed as desensitization of zaprinast-induced DMR response preincubated for 1 h...More data for this Ligand-Target Pair